基本情况：

民族：汉

籍贯： 甘肃民乐

地址：北京右安门外西头条10号

Tel:86-10-83911505(Office)

E-mail:Martinliuer@hotmail.com (or) Martinliuer@yahoo.com

出生年月： 1971 年 12 月

简介：兰州医学院学士、硕士， 2001 年毕业于华中科技大学同济医学院（原同济医科大学）公共卫生学院，获医学博士学位，同年十月进入中国疾病预防控制中心环境与健康相关产品安全所进行博士后研究工作，于 2004 年 4 月顺利出站，获得博士后证书。现为首都医科大学公共卫生于家庭医学学院预防医学系劳卫 - 环卫教研组副教授。

教育及工作经历：

1989.9-1994.7 兰州医学院预防医学系大学本科

1994.9-1995.7 甘肃省张掖地区人事处干部

1995.9-1998.7 兰州医学院环境卫生专业硕士研究生

1998.9-2001.7 华中科技大学同济医学院环境卫生和劳动卫生专业博士研究生

2001.10-2004.7 中国疾病预防控制中心环境所博士后研究

2004.8 至今 首都医科大学公共卫生与家庭医学学院副教授

科研情况：（详细介绍）

1995.8-1998.8 ，进行“乳状液膜新技术在医学生物学领域的研究”，首次将该技术引入医学生物学领域，在进行乳状液膜对氨基酸的提取时，获得巨大成功，该项目获得 1995 年自然科学基金资助，并先后发表论文 4 篇，其中两片发表在国外权威期刊；同时，还将该技术应用于水体污染的治理，进行含酚废水中酚等有机物的净化，取得明显效果，此研究也获得 1997 年省自然科学基金资助。同时还参与甘肃省定西地区 “121 雨水集流工程项目的调查与评估 ” 。

1998.9-2001.8 ，先后参与实施国家“九五”科技攻关计划“武汉东湖水体污染及其预警研究”和国家自然科学基金“水体氮、磷污染及其生物去除技术研究”，主要承担东湖氮污染状况调查和水中“三氮”污染物的生物去除研究。研究过程共完成论文 6 篇，其中两篇已经发表，其他也将陆续发表。

2001.10-2004.4, 进行室内空气污染及其危险度评价研究，主要参与国家“十五”科技攻关项目 ----- “室内空气污染及其治理的研究”和科技部“十五”公益项目研究 ----“ 装修材料所致的室内空气污染及其危险毒评价研究 ” ，主要承担“装饰材料中挥发性有机物的细胞毒性研究”，内容涉及细胞毒理、分子毒理，共完成 10 万字的博士后工作报告

2004.8- 现在 目前主要从事北京居室空气污染及其模式研究、室内化学污染物的细胞和分子毒理研究和室内空气污染及其治理等方面的研究工作。

科研技能：

1.本人长期从事环境卫生专业研究工作，具有较为丰富的科研工作经验，掌握了毒力学、细胞生物学、分子生物学、流行病学和实验动物学等学科的基本技能与操作，能独立的开展各项科研工作。

2. 曾后参与和实施国家“九五”科技攻关项目、国家“十五”科技攻关项目、自然科学基金项目和科技部“十五”公益项目研究工作，具有承担和实施重大科研项目的经验和能力。

3.曾参与“香烟烟气毒性评价研究” , “贫铀细胞毒性及慢性转化研究”，“烹调油烟细胞毒性和分子毒性研究”等研究工作，具有对各类化学物进行危险毒评价的经验和技能。

4.专业外语水平尚佳，能够以国外同行专家流利交流，能撰写较高质量的英文科技论文；能够协调和指导研究生进行相关研究，具有良好的课题实施、组织能力和团队协作精神。

　已发表的文章： Publication
1.Liu Dongshan, Luo Qifang. Variation and transformation of nitrogen pollutants in source and tap water of D-lake (in Chinese). Journal of Hygiene Research, 2002,31(3): 160-163

2.Liu Dongshan, Luo Qifang. Distribution and Role of Denitrifing, Nitrifying, Nitrosation and Ammonnifing Bacteria in East Lake (in Chinese). Environmental Science, 2002,23(3): 29-35

3.Liu Xingrong, Liu Dongshan. Mass transfer resistance analysis of L-tryptophan extraction in an emulsion liquid membrane system. Separation Science and Technology, 2000,35(16): 2707-2724

4.Gaoliang, Liu Dongshan. Extraction of L- cysteine by A Liquid Emulsion Membrane Technique (in Chinese). Technology of Water Treatment, 2000,26(2): 76~81

5.Liu Xingrong, Liu Dongshan. Modeling of Facilitated Transport of Phenylalanine by Emulsion Liquid Membrane with Di(2-ethylhexy) phosphoric Acid as a Carrier. Separation Science and Technology, 1998,33 (16): 2597~2608

6.Liu Xingrong, Liu Dongshan. Extraction of L-phenylalanine by A Liquid Emulsion Membrane Technique (in Chinese). Technology of Water Treatment, 1997,23(4): 217~221

7.Liu Dongshan, Liangchaoke. Evaluation of the genotoxic potential of some volatile organic compounds (VOC) with the comet assay, colony forming ability assay and the HPRT gene mutation assay. (Prepared)

8.Liu Dongshan,Jin Yinglong.Malignant transformation of human bronchial epithelial cell (BEAS-2B) induced by volatile organic compounds (VOC). (Prepared)



CURRICULUM VITAE

Personal information

Name:
LIU Dongshan (Martin)

Sex:
Male

Birth
December 4, 1971, Gansu Province , P.R.C.

Citizenship
P.R. China

Health
Good

Marital status
Married to ZHANG Guizhi , daughter LIU Xintian, born in 2001

Leisure interests
Sports, Classic music,Chinese Painting, Culture and history


Current Address

1040#, East 10 th building

The National Defense University of PLA

No.83 Fuxing Road , Haidian District

Beijng 100853　P. R. China

Telephone: 86-10-63051463(O)

E-mail: Martinliuer @ hotmail.com

　　　　Martinliuer @ yahoo.com

Education and Training
High School:

First Middle School , Minle County, Gansu Province, 1986-89

Graduation: July 1989(with "Group A Honors")

Course of special interest: Biology, English

Activities: English speaking and handwriting contest

Honors: Award for Moral, Academic, and Physical Excellence

College:

Lanzhou Medical College , Lanzhou , Gansu Province , China , 1989- 94

Graduation: July 1994

Major: Preventive medicine and public health

Degree: B. Sc. (medical degree)

Activities: Chinese Painting club, English club, monitor of class

Major courses: Biology, Microbiology, Physiology, Biochemistry, Anatomy, Pathology, Cytobiology, Molecular Biology, Immunology, Genetics, Pharmacology, Clinical Medicine (Internal Medicine Surgery) and Preventive Medicine etc.,

Lanzhou Medical College , Lanzhou , Gansu Province , China ,1995- 98

Graduation: July 1998

Thesis topic : Extraction of Amino Acid by A Liquid Emulsion Membrane Technique

Major : Environmental Health

Degree: M. Sc.

Activities : the debate of college, vice-president of the postgraduate union

School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. 1998 – 2001

Graduation : July 2001

Thesis topic : Study on Distribution, Variation and Transformation of Nitrogen Pollutants

In Donghu Lake and Nitrogen Removal Using Biodenitrification Technology

By Immobilized Cell

Major : Occupational and environmental health.

Degree: Ph.D.

( Tongji Medical College , the previous Tongji Med. Univ., is one of the top three Med. Colleges in China , which was founded in Shanghai in 1907. Her school of public health instituted in 1953 is the biggest and best education and research institution on public health in China. ).

Further training:

Postdoctoral Fellow -- Institute for Environmental Health and Related Product Safety* Chinese Center for Disease Control and Prevention (former Chinese Academy of Preventive Medicine , CAPM), Beijing . (Oct., 2001- Jun.,2004)

Work Experiences

Oct. ,2004 – present Working as a vice-professor of Public Health and Family Medical College of Capital University of Medical Sciences

Oct. ,2001 – Jun.,2004 working as a postdoctoral fellow in the Institute for Environmental Health and Related Product Safety, Chinese Center for Disease Control and Prevention (China CDC), Beijing .

Sep., 1998 – Jul., 2001 I working as a Ph.D. candidate in the Lab of Environmental Engineering, Institute of Environment Medicine, Tongji Medical College of Huazhong University of Science and Technology, Wuhan. My major is in Occupational and environmental health . In June of 2001, I passed the thesis oral defense with full “A” score from seven experts and obtained my Ph.D. degree.

Sep., 1995 – Jul. 1998 working as M.S. candidate in the Lab of Toxicology, Department of Preventive Medicine, Lanzhou Medical College , Lanzhou , China

Sep, 1989 – Jul, 1994 working as B.S. candidate in Lanzhou Medical College, and systematically trained in Anatomy, Biology, Biochemistry, Microbiology, Immunology, Pathology, Cytobiology, Molecular Biology, Genetics, Pharmacology, Internal Medicine, Surgery, and other subjects in clinical medicine and preventive medicine during the college period at Lanzhou Medical College, and worked as an intern for half a year. Finally I obtained my Medical Degree in 1994.

Research & Projects （detail）

2004-present

（1） Study on the indoor air pollution and control in Beijing , China

（2）Study on the cellular and molecular toxicity of chemical carcinogen and the mechanisms of carcinogenesis

2001-2004 （detail）

（1） Cellular and Molecular mechanisms of volatile organic compounds (VOCs) toxicity in/from decorative & building materials.

（2） Immortalization of human fetal bronchial epithelial cells transfected by telomerse catalysis subunit (human telomerase reverse transcriptase, hTERT) .

（3）The cellular and molecular mechanisms of depleted uranium toxicity using two in vitro models (BEAS-2B cell line and BEP2D cell line) and an animal model (rat).

1998-2001: （detail）

Contamination and Transformation of Nitrogen in Water of Donghu Lake and Nitrogen Removal using Biodenitrification Technology by Immobilized cells.

（1）The existing forms of nitrogen and their polluting pathways, characters, transformations in water of Donghu Lake were investigated. The study showed that there were three major ion forms of nitrogen, including ammonium, nitrite and nitrate, which could transformed each other in certain conditions.

（2）Based on the former practice, a experiment on nitrogen transformation was carried out. The effects of different operational conditions were studied.

（3）In order to eliminate the nitrogen pollution, four nitrogen bacteria were cultured, screened, enriched and finally immobilized with PVA and sodium alginate alga. The immobilized bacteria were more effective to remove nitrogen than free bacteria. By artificial inducement we can obtain highly efficient nitrifers and denitrifers which modeling study had verified to be feasible. The nitrifying effectiveness, denitrifying effectiveness and their affecting factors were also studied and the application of the immobilized bacteria technology was further discussed as well.

1995-1998:

Application of the Liquid Emulsion Membrane in Biological and Medical Fields.

(1) The extraction of amino acid through liquid emulsion membrane (LEM) was studied. The studies were carried out by utilizing the difference of H +. concentration or OH-concentration between the external and internal phases as the driving force. Using tri-n-octy-lamine, di-n-octy-lamine and n-octy-lamine as the cation or anion carriers. Span 80 as the surfactant, liquid paraffin as a membrane phase additive (cosurfacant), meanwhile, using L-lysine,L-phenylalanine , L-glutamic acid and L-cysteine as the model solutes, the experiments were preformed under various operation conditions.

(2) A mathematics model, which considered the external phase mass transfer resistance, interfacial reaction, diffusion throughout the member and membrane swelling and breakage, was established to simulate and explain the extraction process. The proposed model explained the transport behavior of the solutes.

(3) Having compared with the behavior of different carriers, different driving forces and different amino acids, it was found that different carries had different transport behaviors to a certain amino acid. And the same carries with different driving force also had different transport behaviors, i.e. the cation - type transport of an amino acid faster than anion - type transport one.

(4) It was found that the efficiency of extraction was, in some degree, directly to the concentration of carried and concentration of H/OH in external phase. The extraction efficiency was also connected with the emulsion- stabilizing surfactant, co surfactant and other ingredients.

Conclusion: The experimental results showed that the presented model was a good agreement with the extraction process and valid for simulating the facilitated transport and valid for simulating the facilitated transport of amino acids with LEM under various experimental conditions.

Technical Skills
Medicine:

Excellent education and training background on basic and clinical medicine, and experienced with clinical practice.

Laboratory:

1. Animal Experiment and Surgical Operation Skills

2. Conventional biochemical & pharmacological experiment and special toxicological experiment skills

3. Cell and tissue culture

4. Immuno-cytochemistry & Immuno-histochemistry

5. Conventional Cytobiology and Molecular Biology experiment skills

6. Molecular hybridization

7. RT-PCR, western blot, Northern blot, southern blot

8. DNA Recombination, cDNA Cloning, Sequencing

9. Common statistical & analytical methods

10. Analytical chemistry techniques, environmental measurement and risk assessment

Honors

Award for Moral, Academic, and Physical Excellence and receive 5 special-grade Scholarships during past five years of college.

The top one in all examinees in the Graduate Admission Exam at Lanzhou Medical College in 1995.

Award for the outstanding postgraduate of Lanzhou Medical College in 1997.

Receive the Gold Union Scholarship of Hong Kong in 1999.

Award for Excellent Doctor Candidate of Tongji Medical University and receive Special Scholarship in 2001

Successful for the official Postdoctoral Fellowship Program of Chinese Center for Disease Control and Prevention (former Chinese Academy of Preventive Medicine , CAPM ), Beijing

Publication in English

1.Liu Xingrong, Liu Dongshan. Mass transfer resistance analysis of L-tryptophan extraction in an emulsion liquid membrane system (in English). Separation Science and Technology, 2000,35(16): 2707-2724

2.Liu Xingrong, Liu Dongshan. Modeling of Facilitated Transport of Phenylalanine by Emulsion Liquid Membrane with Di(2-ethylhexy) phosphoric Acid as a Carrier(in English). Separation Science and Technology, 1998,33 (16): 2597~2608

Publication in Chinese

1. Liu Dongshan, Luo Qifang. Variation and transformation of nitrogen pollutants in source and tap water of D-lake. Journal of Hygiene Research, 2002,31(3): 160-163

2. Liu Dongshan, Luo Qifang. Distribution and Role of Denitrifing, Nitrifying, Nitrosation and Ammonnifing Bacteria in East Lake . Environmental Science, 2002,23(3): 29-35

3. Gaoliang, Liu Dongshan. Extraction of L- cysteine by A Liquid Emulsion Membrane Technique (in Chinese). Technology of Water Treatment, 2000,26(2): 76~81

4. Liu Xingrong, Liu Dongshan. Extraction of L-phenylalanine by A Liquid Emulsion Membrane Technique. Technology of Water Treatment, 1997,23(4): 217~221

5. Liu Dongshan, Liangchaoke. Evaluation of the genotoxic potential of some volatile organic compounds (VOC) with the comet assay, colony forming ability assay and the HPRT gene mutation assay. (Prepared)

6. Liu Dongshan,Jin Yinglong.Malignant transformation of human bronchial epithelial cell (BEAS-2B) induced by volatile organic compounds (VOC). (Prepared)